Category Archives: gene duplication
Evolutionary trajectories of new duplicated and putative de novo genes
Completely new protein sequences in genomes can arise by gene duplication or de novo. How does the mechanism of origination influence the fate of the proteins? Do duplicated proteins tend to be retained at higher rates than de novo proteins? … Continue reading
Filed under de novo gene evolution, gene duplication, micropeptide, Uncategorized, yeast
New genes and functional innovation in mammals
Many human genes have counterparts in distant species such as plants or bacteria. This is because they share a common origin, they were invented a long time ago in a primitive cell. However, there are some genes that do not … Continue reading
Filed under de novo gene evolution, gene duplication, mammal, Papers
Increased gain of “low complexity” regulatory domains in duplicated transcription factors
How do duplicated transcription factors, which are initially identical in sequence, specialize to perform diverse functions? We have team up with the group of Susana de la Luna, at the Center for Genomic Regulation (CRG), to try to answer this … Continue reading
Filed under amino acid repeat, gene duplication
