Tag Archives: evolutionary rate

Increased gain of “low complexity” regulatory domains in duplicated transcription factors

How do duplicated transcription factors, which are initially identical in sequence, specialize to perform diverse functions? We have team up with the group of Susana de la Luna, at the Center for Genomic Regulation (CRG), to try to answer this … Continue reading

Leave a Comment

Filed under amino acid repeat, gene duplication

On homology searches by protein Blast and the characterization of the age of genes (revisited)

This month a paper that investigates the power of sequence similarity searches by BLAST to classify genes into different age classes (phylostratigraphy), Phylostratigraphic bias creates spurious patterns of genome evolution (Moyers and Zhang, Uni Michigan) states that the method substantially … Continue reading

Leave a Comment

Filed under de novo gene evolution, Papers