Tag Archives: de novo gene evolution

“lncRNAs as a source of new peptides” among the most viewed posts in Haldane’s sieve 2014

Our post on the paper “Long non-coding RNAs as a source of new peptides” was among the most viewed in Haldane’s sieve during 2014. Following publication of the preprint in Arxiv and the related post in May 2014, it became … Continue reading

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“Long non-coding RNAs as a source of new peptides” published in eLife

Abstract Deep transcriptome sequencing has revealed the existence of many transcripts that lack long or conserved open reading frames (ORFs) and which have been termed long non-coding RNAs (lncRNAs). The vast majority of lncRNAs are lineage-specific and do not yet … Continue reading

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Filed under de novo gene evolution, lncRNA, Papers

Video on the evolution of orphan genes

The video explains how new genes originate. Whereas many genes are formed by duplication of preexisting genes others arise directly from genomic regions by still poorly understood mechanisms. The latter genes are called orphan genes and represent radically new evolutionary … Continue reading

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