A new issue in Experimental Cell Research is dedicated to different aspects of an extensive group of proteins known as micropeptides, many of which still remain hidden in genomes. These peptides are translated from open reading frames shorter than 100 amino acids that are present in transcripts that are currently annotated as non-coding or in the 5′UTR of protein-coding genes. We have written a short piece about our favorite subject, how small ORFs in lncRNAs can evolve into new functional proteins.
You can read it all here: The hidden world of non-canonical ORFs
