Category Archives: Papers
PALO paper published at GBE: Improving genome-wide scans of positive selection by using protein isoforms of similar length
José Luis Villanueva-Cañas, Steve Laurie and M.Mar Albà Large-scale evolutionary studies often require the automated construction of alignments of a large number of homologous gene families. The majority of eukaryotic genes can produce different transcripts due to alternative splicing or … Continue reading
ALL ALONE Genes from nowhere: Orphans with a surprising story 16 January 2013 by Helen Pilcher NOT having any family is tough. Often unappreciated and uncomfortably different, orphans have to fight to fit in and battle against the odds to … Continue reading
A paper entitled “Dissecting the role of low-complexity sequences in the evolution of vertebrate proteins” by Núria Radó-Trilla and M.Mar Albà, has been accepted for publication at BMC Evolutionary Biology. Abstract Low-complexity regions (LCRs) in proteins are tracts that are … Continue reading
The paper “Structure and age jointly influence rates of protein evolution”, in collaboration with J.Plotkin lab, accepted in Plos Computational Biology.
ABSTRACT: What factors determine a protein’s rate of evolution are still under debate. Especially unclear is the relative role of intrinsic factors of present-day proteins versus historical factors such as protein age. Here we study the interplay of structural properties … Continue reading
Medya’s work on the UL1 protein from human cytomegalovirus has been published in Journal of Virology abstract Tweet