Publications

2010

Toll-Riera, M.,Laurie, S., Albà, M.M. (2010) Lineage-specific Variation in Intensity of Natural Selection in Mammals. Molecular Biology and Evolution, Aug 5. [Epub ahead of print]. [Abstract]

Mularoni, L., Ledda, A., Toll-Riera, M., Albà, M.M. (2010) Natural selection drives the accumulation of amino acid tandem repeats in human proteins. Genome Research, 20: 745-754. [Abstract]

Farré, D., Albà, M.M. (2010) Heterogeneous patterns of gene expression diversification in mammalian gene duplicates. Molecular Biology and Evolution, 27:325-335. [Abstract] [Evaluated by the Faculty of 1000]

2009

Albà, M.M. Temporal aspects of gene evolution. Año Darwin, SESBE, 2009. [PDF]

Toll-Riera, M., Castelo, R., Bellora, N., Albà, M.M. (2009) Evolution of primate orphan proteins. Biochemical Society Transactions, 37:778-782. [Abstract]

Salichs, E., Ledda, A., Mularoni, L., Albà, M.M., de la Luna, S. (2009) Genome-wide analysis of histidine repeats reveals their role in the localization of human proteins to the nuclear speckles compartment. Plos Genetics, 5: e1000397. [Manuscript]

Rodilla, V., Villanueva, A., Obrador-Hevia, A., Robert-Moreno, A., Fernández-Majada, V., Grilli, A., López-Bigas, N., Bellora, N., Albà, M.M., Torres, F., Duñach, M., Sanjuan, X., González, S., Gridley, T., Capella, G., Bigas, A., Espinosa, Ll. (2009) Jagged1 is the pathological link between Wnt and Notch pathways in colorectal cancer. Proceedings of the National Academy of Sciences USA, 106:6315-6320. [Abstract]

Toll-Riera, M., Bosch, N., Bellora, N., Castelo, R., Armengol,Ll., Estivill, X., Albà, M.M. (2009) Origin of primate orphan genes: a comparative genomics approach. Molecular Biology and Evolution, 26:603-612. [Abstract]

2008

Toll-Riera, M., Castresana, J., Albà, M.M. (2008) Accelerated Evolution of Genes of Recent Origin. Evolutionary Biology from Concept to Application (Ed. Pontarotti). Springer. [Abstract] [PDF]

Mularoni, L., Toll-Riera, M., Albà, M.M. (2008) Comparative Genetics of Trinucleotide Repeats in the Human and Ape Genomes. Handbook of Human Molecular Evolution 2, pp. 677-686. (Ed.Hildegard Kehrer-Sawatzki & David N. Cooper). John Wiley & Sons, Ltd: Chichester. [link to Book]

Mularoni, L., Toll-Riera, M., Albà, M.M. (2008) Comparative Genetics of Trinucleotide Repeats in the Human and Ape Genomes. Encyclopedia of Life Sciences. John Wiley & Sons Ltd: Chichester. [PDF]

Racz, I., Nadal, X., Alferink, J., Baños, J.E., Rehnelt, J., Martin, M., Pintado, B., Gutierrez-Adan, A., Sanguino, E., Bellora, N., Manzanares, J., Zimmer, A., Maldonado, R. (2008) Interferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain. Journal of Neuroscience , 28: 12136-12145. [Abstract]

2007

Bellora, N., Farré, D., Albà, M.M. (2007) Positional bias of general and tissue-specific regulatory motifs in mouse promoters. BMC Genomics, Vol. 8:459. [Abstract] [PDF]

Albà,M.M., Tompa, P., Veitia, R.A. (2007) Amino-acid repeats and the structure and evolution of proteins. In Gene and Protein Evolution, Genome Dynamics (Ed. J-N. Volff, Basel, Karger), Vol. 3:119-130. [Abstract]

Farré, D.,Bellora, N., Mularoni, L., Messeguer, X., Albà, M.M. (2007) Housekeeping genes tend to show reduced upstream sequene conservation. Genome Biology, 8:R140. [Abstract] [PDF]

Albà, M.M., Castresana, L. (2007) On homology searches by protein Blast and the characterization of the age of genes. BMC Evolutionary Biology, 7:53. [Abstract] [PDF]

Mularoni, L., Veitia, R.A., Albà, M.M. (2007) Highly constrained proteins contain an unexpectedly large number of amino acid tandem repeats. Genomics, Vol. 89:316-325. [Abstract] [PDF]

Bellora, N., Farré, D., Albà, M.M. (2007) PEAKS: Identification of regulatory motifs by their position in DNA sequences. Bioinformatics, 23:243-244. [Abstract][PDF]

2006

Furney, S.J., Albà, M.M., López-Bigas, N. (2006). Differences in the evolutionary history of disease genes affected by dominant or recessive mutations. BMC Genomics, Vol. 7: 165. [PDF]

Mularoni, L., Guigó, R., Albà, M.M. (2006). Mutation patterns of amino acid tandem repeats in the human proteome. Genome Biology, Vol. 7:R33. [PDF]

Blanco E.,Farré, D., Albà, M.M., Messeguer, X., Guigó, R. (2006). ABS: a database of annotated regulatory binding sites from orthologous promoters. Nucleic Acids Research, Vol. 34: D63-D67. [PDF]

2005

Albà, M.M., Castresana, J. (2005). Inverse Relationship between Evolutionary Rate and Age of Mammalian Genes. Molecular Biology and Evolution, Vol. 22: 598-606. [PDF]

2004

Castresana, J., Guigó, R.,Albà,M.M.(2004).Clustering of genes coding for DNA binding proteins in a region of atypical evolution of the human genome. Journal of Molecular Evolution, Vol. 59: 72-79. [PDF]

Huang et al. (including Albà, M.M.) (2004) Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes. Genome Biology, Vol. 5: R47. [PDF]

Gendra, E., Moreno, A., Albà, M.M., Pagès, M. (2004) Interaction of the plant glycine-rich RNA binding protein MA16 with a novel nucleolar DEAD box RNA helicase protein from Zea mays. The Plant Journal, Vol. 38: 875 - 886. [PDF]

Gibbs et al. (including Albà, M.M.) (2004). Genome Sequence of the Brown Norway Rat Yields Insights into Mammalian Evolution. Nature, Vol. 428: 493-521. [link to issue]

Albà, M.M., Guigó, R. (2004). Comparative analysis of amino acid repeats in rodents and humans. Genome Research, Vol. 14: 549-554. [PDF]

2003

Farré, D., Roset, R., Huerta, M., Adsuara, J.E., Roselló, L., Albà, M.M., Messeguer, X. (2003). Identification of patterns in biological sequences at the ALGGEN server: PROMO and  MALGEN. Nucleic Acids Research, Vol. 31: 3651-3653. [PDF]

2002
Messeguer, X., Escudero, R., Farré D., Núñez O., Martínez J., Albà, M.M. (2002). PROMO: detection of known transcription regulatory elements using species-tailored searches. Bioinformatics, Vol. 18: 333-334. [PDF]